诺华招聘生物信息学博士后，坐标麻省（微信文章未删减版）

药明康德/报道

Job Description

We are seeking a highly motivated Bioinformatics Scientist/Computational Biologist to join our team to advance the development and implementation of genomic methods including genome editing off-target analysis, gene expression profiling analysis, single cell RNA-seq/CITE-seq analysis, and epigenetic analysis with the goal of advancing drug discovery with our disease area partners.

The Genomic Sciences Home within the NIBR’s Chemical Biology and Therapeutics (CBT) drug discovery platform applies innovative genomic technology approaches for the identification of new drug targets and the elucidation of the mode of action of novel small molecules and genomic reagents. In this framework, our team applies sequencing-based molecular profiling technologies for the identification of disease-associated genes and pathways, the discovery of new drug targets by functional genomic screening, the exploration of tissue biology by studying complex cell populations at the single cell level, and the development and characterization of new breakthrough cell and gene therapy reagents.

Specific job responsibilities include:

• Collaborate on the design, development, and implementation of new genomic technologies (e.g. scRNA-seq, optical genome mapping) and applications (e.g. CRISPR off-target analysis, CROP-seq).

• In collaboration with CBT and disease area partners lead analyses of genomic data sets.

• Develop, evaluate and implement innovative analytical solutions for existing and new genomic applications

• Communicate key findings to key partners within CBT and disease area partners.

EEO Statement

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.

Minimum requirements

• M.Sc. with more than 5 years industry experience or Ph.D. with postdoc experience in bioinformatics, computational biology, genomics, computer science, or related fields.

• Solid understanding of genomic technologies (e.g. sequencing, genome editing) and related data analysis (e.g. off-target analysis, RNA-seq, scRNA-seq, genome assembly, variant calling)

• Detail-oriented, self-motivated and scientifically driven with proficient reasoning skills in experimental design, data analysis and interpretation

• Effective prioritization among multiple projects

• Excellent interpersonal and communication skills

• Proven ability to work effectively within a team

• Proficiency with Unix, high-performance computing, scripting languages (e.g. bash, python, R), and standard bioinformatics/sequencing analysis software

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