但是，目前这个想法还没有被证实，如果下一步的申请被批准，Bhatti教授就会实施这个计划，并追踪褪黑激素的补充对DNA的损伤、嗜睡、警觉性、整体健康的影响[1]。
想想看，到时候如果给晚上工作的人补充了褪黑激素，DNA损伤能被修复的话，那就厉害了！简直是造福了晚上作死不睡和被迫不能睡的人啊！
不过，在这之前，Bhatti教授建议晚上工作的人应该注意健康，保持良好的生活方式，保持良好的睡眠，并且注意饮食和锻炼，积极抵御癌症风险[1]。
所以啊，晚上不得不工作的人，请你更要好好生活！那些和我一样作死晚睡的人，珍爱生命，让我们从按时睡觉、修复DNA做起！
参考资料
1.https://www.fredhutch.org/en/news/center-news/2017/06/study-on-night-shift-work-day-sleep-cancer-connection.html
2.https://academic.oup.com/jnci/article/93/20/1557/2519561/Night-Shift-Work-Light-at-Night-and-Risk-of-Breast
3.http://www.medicalnewstoday.com/articles/312064.php
4.Wu LL, Chiou CC, Chang PY, et al. Urinary 8-OHdG: a marker of oxidative stress to DNA and a risk factor for cancer, atherosclerosis and diabetics. Clin Chim Acta 2004;339:1–9.
5.Cooke MS, Henderson PT, Evans MD. Sources of extracellular, oxidatively-modified DNA lesions: implications for their measurement in urine. J Clin Biochem Nutr 2009;45:255–70.
6.Bhatti P, Mirick DK, Randolph TW, et al. Oxidative DNA damage during sleep periods among nightshift workers. Occup Environ Med 2016;73:537–44
7.http://oem.bmj.com/lookup/doi/10.1136/oemed-2017-104414#
8.Davanipour Z, Poulsen HE, Weimann A, et al. Endogenous melatonin and oxidatively damaged guanine in DNA. BMC Endocr Disord 2009;9:22.
9.Bennukul K, Numkliang S, Leardkamolkarn V. Melatonin attenuates cisplatin-induced HepG2 cell death via the regulation of mTOR and ERCC1 expressions. World J Hepatol 2014;6:230–42.
10.Sun FY, Lin X, Mao LZ, et al. Neuroprotection by melatonin against ischemic neuronal injury associated with modulation of DNA damage and repair in the rat following a transient cerebral ischemia. J Pineal Res 2002;33:48–56.
11.Sliwinski T, Rozej W, Morawiec-Bajda A, et al. Protective action of melatonin against oxidative DNA damage: chemical inactivation versus base-excision repair. Mutat Res 2007;634:220–7.
